Endocrine Abstracts

A 27-year-old woman with had sweating flushing attacks for three years prior to pregnancy, but did not follow with any medical examination. At 12th gestational week, hypertension was detected and alpha-methyldopa was started, no abnormal findings were found in the routine examinations, in the 24-h holter study, blood pressure values (using alpha-methyldopa) were found to be higher than 144/99 (general), 147/101 (awake) and 134/92 mmHg (sleep). 24-hour urinary levels of catecho...

A 60-year-old male patient who presented with left hip and knee pain was found to be compatible with primary hyperparathyroidism (PTH:2233 pg/ml, calcium: 15.7 mg/dl, phosphorus: 2.9 mg/dl creatinin:1.99 mg/dl, 25-OH-D:9.7 μg/l, ALP:532 mU/ml). Bone grafts of the patient showed multiple lytic lesions in the pelvis, cranium and long-bones. Neck ultrasonography showed hypoechoic solid nodule with cystic areas, 2×2 cm with size in the left thyroid gland inferior region ...

Background: Sitagliptin, unlike the some major antihyperglycemic drugs, is not associated with weight gain and has neutral effects on body weight. It is unclear whether sitagliptin treatment alters immune functions and insulin resistance in people with type 2 diabetes. The aim of the present study was to assess the effect of sitagliptin on insulin resistance and immune functions in patients with type 2 diabetes mellitus.Methods: Twenty type 2 diabetic su...

Although serum calcium (Ca), phosphorus and parathyroid hormone (PTH) levels tend to normalize after successful kidney transplantation (KT), persistent hyperparathyroidism (PHPT) can have deleterious effects on graft function. We aimed to evaluate the effect of parathyroidectomy (PTx) on graft function in recipients after KT.Methods: This retrospective study conducted in 319 adult KT recipients. PHPT is defined as serum corrected Ca level >10.2 mg/dl...

After a successful kidney transplant, the nutrition of patients is improved and they gain weight. Increased appetite due to medication, age of transplant, gender, race, pre-transplant obesity story and dialysis type increase the obesity frequency. We aimed to evaluate the effect of gender on nutrition and exercise habits on transplant recipients.Methods: Stable patients were divided into two groups according to gender: 29 males and 33 females. Their nutr...

Introduction: Hyalinizing trabecular adenomas (HTA) of the thyroid gland is a rare neoplasm of follicular cell origin. HTA can be present as a thyroid nodule or incidental finding in a thyroidectomy specimen. HTA is generally accepted to be a benign tumor, but their cytological features can be similar to those of papillary thyroid carcinoma (PTC).Case report: A 59 year old woman, who had cholangiocellular carcinoma, admitted to our institution with a sol...

Introduction: Hypervitaminosis D is a rarely reported condition. It may be observed more frequently because of the recent increase in supplement use of vitamin D. Herein, we report a case of vitamin D intoxication which was the first case with this high level of calcium as we searched the literature.Case report: A 57-year old hypertensive woman admitted to our emergency room with symptoms of constipation, loss of appetite and confusion. Blood pressure, h...

Aim: Delayed gastric emptying affects a substantial proportion of patients with long-standing diabetes. On the other hand changes in gastric incretin hormones also play an important role in the pathophysiology of diabetes. In our study, we aimed to investigate the incidence of gastrointestinal disease in patients with newly diagnosed diabetes and pre-diabetes.Methods: A total of 73 patients with newly diagnosed pre-diabetes and diabetes were included in ...

Aim: Metformin is usually well-tolerated and commonly used oral-antidiabetic in type-2 diabetes and pre-diabetes. The most common side effects are gastrointestinal (GI) ones. It is proposed that, extended-release form of metformin has less gastrointestinal side effects. We aimed to compare the extended-release and normal-release form metformin in type-2 diabetic and prediabetic patients for gastrointestinal tolerability, weight effect and glycemic control.<p class="abstext...

Introduction: SGLT2 inhibitors have been an important step in the treatment of diabetes. With numerous controlled experimental studies of these antidiabetic drugs, evaluation of real-life data after entry into clinical practice is an important condition. In our study, it was aimed to evaluate short-term results on glycemic control and weight loss in a narrow group of patients in the single tertiary medical center.Methods: The study was retrospectively de...